Macrocyclic lactam prokinetic agents

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549267, C07D40714, C07D41314

Patent

active

055234186

ABSTRACT:
Macrocylic lactam compounds of formula (i) ##STR1## and pharmaceutically acceptable salts thereof, wherein A is selected from ##STR2## also disclosed are synthetic processes and intermediates useful in the preparation of the compounds of the invention, as well as compositions containing the same and methods for their use in stimulating contractile motion of the gastrointestinal tract.

REFERENCES:
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patent: 4512982 (1985-04-01), Hauske
patent: 4677097 (1987-06-01), Omura et al.
patent: 4920102 (1990-04-01), Gidda et al.
patent: 4958010 (1990-09-01), Kadow et al.
patent: 5106961 (1992-04-01), Kirst et al.
patent: 5189159 (1993-02-01), Wilkening
patent: 5202434 (1993-04-01), Wilkening

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