Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-08-10
2011-11-29
Solola, Taofiq A (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S109000
Reexamination Certificate
active
08067412
ABSTRACT:
Disclosed are macrocyclic compounds of formulae I-V, which are analogs of the pochonin resorcylic acid lactones, and processes for the preparation of the compounds. The compounds disclosed are useful as inhibitors of kinases and Heat Shock Protein 90 (HSP 90). Also disclosed are pharmaceutical compositions comprising an effective kinase-inhibiting amount or an effective HSP90-inhibiting amount of the compounds and methods for the treatment of disorders that are mediated by kinases and HSP90.
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Supplementary European Search Report based on European Patent Application No. EP 07811232, mailed on Sep. 23, 2010.
Barluenga Sofia
Karplus Martin
Winssinger Nicolas
Cooley LLP
Le Centre National de la Recherche Scientifique
Solola Taofiq A
Universite de Strasbourg
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