Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1991-01-29
1993-03-23
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514602, A61K 31185
Patent
active
051964520
ABSTRACT:
A compound and method for inhibiting cell infection by an enveloped virus. The compound is a macrocyclic chromotropic acid derivative which can be substituted at a variety of naphthalene ring and bridge positions. The compound may be administered parenterally, orally, or topically for treating infection by enveloped viruses.
REFERENCES:
Grollman, A. P. and Horwitz, S. B., in "Drug Design" (E. J. Ariens, Ed.) vol. II, Chapter 7, pp. 261-272, Academic Press (1971).
Poh, B-L and Lim, C. S., Tetrahedron 46, No. 10 (1990) 3651-3658.
Poh, B-L et al., Tetrahedron 46, No. 12 (1990) 4379-4386.
Poh, B-L et al., Tetrahedron 30, No. 8 (1989) 1005-1008.
CA 75:72945h Akerfeldt et al. 1971.
Hwang Kou M.
Liu Su-Ying
Qi You M.
Dehlinger Peter J.
Genelabs Incorporated
Stratford Carol A.
Travers Russell
Waddell Frederick E.
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