Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-03-14
1996-10-08
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514183, 514291, 514411, C07D49116, A61K 31395
Patent
active
055631720
ABSTRACT:
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antiinflammatory and antiproliferative activity, as well as the ability to reverse chemotherapeutic drug resistance.
REFERENCES:
patent: 5162334 (1992-11-01), Goulet et al.
patent: 5189042 (1993-02-01), Goulet et al.
patent: 5250678 (1993-10-01), Goulet et al.
patent: 5252732 (1993-10-01), Sinclair et al.
Luly Jay R.
Or Yat S.
Wagner Rolf
Abbott Laboratories
Bond Robert T.
Crowley Steven R.
Danckers Andreas M.
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