Macrocycles for the treatment of cancer

Details Macrocycles for the treatment of cancer Macrocycles for the treatment of cancer

2004-09-27

2010-10-05

Anderson, Rebecca L (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C549S274000

Reexamination Certificate

active

07807710

ABSTRACT:
The invention relates to the novel macrocycles of general formula (I) and to their use in the treatment of tumor diseases.

REFERENCES:
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patent: WO-93/10121 (1993-05-01), None
patent: WO-99/02514 (1999-01-01), None
patent: WO 02/32844 (2002-04-01), None
Vippagunta, et al. Advanced Drug Delivery Reviews 48 (2001) pp. 3-26.
Cancer and Metastasis Reviews (1998), 17(1), 91-106.
Science (1999), vol. 286, 531-537.
Cancer [online], [retrieved on Jul. 6, 2007]. Retrieved from the internet, URL http://www.nlm.nih.gov/medlineplus/cancer.html>.
Cancer [online], [retrieved on Jul. 6, 2007]. Retrieved from the internet, URL; http://en.wikipedia.org/wiki/Cancer.
Greene, T.W. & Wuts, P.G.M.,Protective Groups in Organic Synthesis, Third Ed., John Wiley & Sons, New York (1999), pp. 494-648.
Mulzer et al.,C.R. Chimie, 11: 1336-1368 (2008).
Nicolaou et al.,Angew. Chem. Intl. Ed. Engl., 35 (20): 2399-2401 (1996).
Smith, M. B. & March J.,March's Advanced Organic Chemistry, Fifth Ed., John Wiley & Sons, Inc., New York (2001), pp. 499-501 and 775-777.

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