Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-07-15
2009-06-30
Shiao, Rei-Tsang (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S367000, C514S431000, C514S450000, C548S180000, C548S204000, C549S010000, C549S266000
Reexamination Certificate
active
07553859
ABSTRACT:
The present invention relates to new Macro-cycles of Formula (I), and their use for the treatment of cancer.
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Nicolaou et al. “Chemical Biology of Epothilones” Angew. Chem. Int. Ed. 1998, vol. 37, pp. 2014-2045.
Florsheimer et al. “Epothilones and their analogues—a new class of promising microtubule inhibitors” Expert Opin. Ther. Patents 2001, vol. 11, Iss 6, pp. 951-968.
Patani et al. “Bioisosterism: A Rational Approach in Drug Design” Chem. Rev. 1996, vol. 96, pp. 3147-3176.
Nicolaou, K.C.: “Chemical Biology of Epothilones”,Angewandte Chemie. International Edition., vol. 37, Aug. 1998, pp. 2014-2045.
Hoefle Gerhard
Richter Wolfgang
Frommer & Lawrence & Haug LLP
Gesellschaft fuer Biotechnologische Forschung mbH (GBF)
Kosack Joseph R
Richter Wolfgang
Santucci Ronald R.
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