M-4 and IsoM-4 derivatives their preparation and compositions co

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...

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549292, C07D30930, A61K 31365

Patent

active

044799659

ABSTRACT:
Tetrahydro-M-4 and tetrahydro-IsoM-4 hydroxy carboxylic acids of the formula (I): ##STR1## wherein one of R.sup.1 and R.sup.2 represents a hydrogen atom and the other represents a hydroxy group which are useful for inhibiting chloresterol biosynthesis in the liver. The invention also provides pharmaceutical compositions containing said lactone(s).

REFERENCES:
patent: 4346227 (1982-08-01), Terahara et al.
patent: 4361515 (1982-11-01), Terahara et al.

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