M-4 And IsoM-4 derivatives and compositions containing them

Details M-4 And IsoM-4 derivatives and compositions containing them M-4 And IsoM-4 derivatives and compositions containing them

1982-05-05

1984-05-29

Milestone, Norma S.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Synthetic or structurally-modified peptidoglycan or...

549292, C07D30930, A61K 31365

Patent

active

044514816

ABSTRACT:
Dihydro-M-4 and dihydro-IsoM-4 are new compounds which may be prepared by the catalytic hydrogenation of M-4 or IsoM-4 respectively. They, and their salts and esters (which may be prepared by conventional salification or esterification reactions with the parent dihydro-M-4 or dihydro-IsoM-4), are capable of inhibiting cholesterol biosynthesis in the liver and may be formulated, for therapeutic use, with conventional pharmaceutical carriers or diluents.

REFERENCES:
patent: 4346227 (1982-08-01), Terahara et al.
patent: 4361515 (1982-11-01), Terahara et al.

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