Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Preparation composition
Reexamination Certificate
2007-01-24
2008-11-11
Wallenhorst, Maureen M (Department: 1797)
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Preparation composition
C436S008000, C436S010000, C436S018000, C436S063000, C436S073000, C436S079000, C436S164000, C436S166000, C436S174000, C436S175000, C252S408100, C422S073000, C422S082050, C422S082090, C435S002000
Reexamination Certificate
active
07449337
ABSTRACT:
A lytic reagent composition and methods for differential analysis of leukocytes are disclosed. In embodiments, the analysis may utilize optical measurements in flow cytometry based hematology analyzers. The reagent system includes an anionic surfactant in a hypotonic solution, an inorganic buffer to maintain the pH in a range from about 6 to about 10, and optionally a leukocyte stabilizer. The reagent system is used to lyse red blood cells and stabilize the leukocytes to enable multi-part differentiation of leukocytes in a near physiologic pH environment on a flow cytometry based hematology analyzer using axial light loss, light scatter intensity, high-numerical aperture side scatter, and time-of-flight measurements.
REFERENCES:
patent: 4286963 (1981-09-01), Ledis et al.
patent: 4485175 (1984-11-01), Ledis et al.
patent: 4528274 (1985-07-01), Carter et al.
patent: 4637986 (1987-01-01), Brown et al.
patent: 4978624 (1990-12-01), Cremins et al.
patent: 5116539 (1992-05-01), Hamaguchi et al.
patent: 5155044 (1992-10-01), Ledis et al.
patent: 5196346 (1993-03-01), Lefevre et al.
patent: 5384549 (1995-01-01), Araki
patent: 5510267 (1996-04-01), Marshall
patent: 5538893 (1996-07-01), Sakata et al.
patent: 5639630 (1997-06-01), Malin et al.
patent: 5786224 (1998-07-01), Li et al.
patent: 5817518 (1998-10-01), Li et al.
patent: 6200500 (2001-03-01), Ryan
patent: 6210969 (2001-04-01), Li et al.
patent: 6232125 (2001-05-01), Deka et al.
patent: 6630990 (2003-10-01), van't Oever et al.
patent: 6858439 (2005-02-01), Xu et al.
patent: 6869798 (2005-03-01), Crews et al.
patent: 6890756 (2005-05-01), Wu
patent: 2005/0048477 (2005-03-01), Peng et al.
patent: 1706959 (2005-12-01), None
patent: 19941359 (2001-03-01), None
patent: 0 743 519 (1996-11-01), None
patent: 1 004 880 (2000-05-01), None
patent: 0197785 (2001-12-01), None
International Search Report dated Apr. 29, 2008.
Klessig D. F. et al,: “Block to Multiplication of Adenovirus Serotype 2 in Monkey Cells.” J Virol, vol. 16, No. 6, Dec. 1975, pp. 1650-1668, XP002478609.
Anderson, S. A. et al.: “Molecular Cloning of the Glycosomal Malate Dehydrogenase of Trypanosoma Brucei.” Mol Blochem Parasitol, vol. 96, No. 1-2, Oct. 30, 1998, pp. 185-189, XP002478610.
Marie, D., et al.: “DNA/RNA Analysis of Phytoplankton by Flow Cytometry” Current Protocols in Cytometry, vol. 11, No. 12. Jan. 2000 pp. 11.12.1-11.12.14, XP002478611.
Deka Chiranjit
Feng Jianwen
Carter DeLuca Farrell & Schmidt LLP
IDEXX Laboratories, Inc.
Wallenhorst Maureen M
LandOfFree
Lytic reagent and method for leukocytes differential in... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Lytic reagent and method for leukocytes differential in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lytic reagent and method for leukocytes differential in... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4032334