Lytic origin of replication for Epstein-Barr virus (EBV)

Chemistry: molecular biology and microbiology – Vector – per se

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4351721, 4352351, 4351723, 935 27, 935 32, 536 235, C12N 1538, C12N 1564, C12N 700

Patent

active

051946017

ABSTRACT:
The invention provides lymphotrophic herpes virus (preferably EBV) recombinants. The portions of the virus that are responsible for the packaging and lytic phase replication have been isolated and cloned. When used with vectors and hosts containing a segment that controls plasmid replication, they provide a means of carrying foreign genes into B-lymphocytes.

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