Lysolecithin derivatives

Details Lysolecithin derivatives Lysolecithin derivatives

1992-02-07

1994-05-10

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Fatty compounds having an acid moiety which contains the...

554 35, 554 80, 554 81, C07C23300

Patent

active

053109589

ABSTRACT:
A modified biologically active protein consisting essentially of a biologically active protein bonded to lecithin via a covalent linking group and a pharmaceutical composition comprising the modified biologically active protein in a pharmaceutically acceptable carrier. The biologically active proteins include antibodies, superoxide dismutase, insulin and callidinogenase. Lecithin derivatives are also disclosed.

REFERENCES:
patent: 4560599 (1985-12-01), Regen
Biophysics, vol. 28, No. 5, pp. 806-811, 1983, A. A. Shaginyan, et al., "Study of Protein-Lipid Interaction Between Superoxide Dismutase and Lecithin in the Liquid-Crystal Phase in the Presence of Chlorides of Monovalent Metals".
WPIL, 88-341498, & JP-A-63-253031, Oct. 20, 1988.
Biochimica et Biophysica Acta, vol. 649, No. 1, Nov. 1981, pp. 45-57, J. R. Lepock et al., "Interaction of Superoxide Dismutase with Phospholipid Liposomes an Uptake, Spin, Label and Calorimetric Study".

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