Lysing or blocking unwanted cells with IL-2 receptor-specific bi

Details Lysing or blocking unwanted cells with IL-2 receptor-specific bi Lysing or blocking unwanted cells with IL-2 receptor-specific bi

1985-09-05

1991-04-30

Draper, Garnette D.

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

424 851, 424 858, 424 8591, 514 2, 514 8, 514 12, 514 21, 514885, 935106, 935107, 530351, 530387, 530391, 530402, A61K 39395

Patent

active

050116843

ABSTRACT:
A method of lysing unwanted, non-malignant cells in a mammal, the cells having on their surfaces a receptor for a growth factor, and the method including administering to the mammal a cell-lysing amount of a substance characterized in that it has specific affinity for the receptor of the growth factor and has the ability to effect the lysis of the cells.

REFERENCES:
patent: 4359457 (1982-11-01), Neville et al.
patent: 4388309 (1983-06-01), Fabricius
patent: 4440747 (1984-04-01), Neville
patent: 4489710 (1984-12-01), Spitler
patent: 4520226 (1985-05-01), Neville et al.
patent: 4545985 (1985-10-01), Pastan et al.
patent: 4550086 (1985-11-01), Reinherz et al.
patent: 4675382 (1987-06-01), Murphy
Kronke et al, Blood 65(6) 1985, pp. 1416-1421 (abstract only).
Shimizu et al, Cell Struct. and Function, 9, 1984, pp. 203-212.
Vallera et al, Science, vol. 222, 1983, pp. 512-515.
Strong et al, Blood 66(3) 1985, pp. 627-635.
Waldmann, Thomas A., "The Structure, Function, and Expression of Interleukin-2 Receptors on Normal and Malignant Lymphocytes", Science, vol. 232, pp. 727-732, May 9, 1986.
Takahashi et al., (1983) The Lancet pp. 1155-1158.
Williams et al., (1984) J. Immunol. 132 (5), 2330.
Kirkman et al., (1983) Transplantation 36 (6), 620.
Zubler et al., (1984) J. Exper. Med. 160 (4), 1170.
Leonard et al., (1982) Nature 300, 267.
FitzGerald et al., (1984) J. Clin. Invest. 74, 966.
Depper et al., (1983) J. Immunol. 131 (2), 690.

Affiliated with

Also associated with

Rating

Lysing or blocking unwanted cells with IL-2 receptor-specific bi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lysing or blocking unwanted cells with IL-2 receptor-specific bi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lysing or blocking unwanted cells with IL-2 receptor-specific bi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-639517