Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form
Reexamination Certificate
1999-04-23
2001-03-27
Keys, Rosalynd (Department: 1621)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
C424S401000, C424S059000, C424S060000, C424S064000, C514S551000, C514S844000, C560S159000, C554S107000, C554S110000
Reexamination Certificate
active
06207173
ABSTRACT:
FIELD OF THE INVENTION
The subject of the present invention is new lysine derivatives containing an N
&egr;
-alkoxy or N
&egr;
-alkenoxycarbonyl group, their preparation and their use, especially as agents which make it possible to facilitate compaction in cosmetic, pharmaceutical, hygiene or food compositions.
BACKGROUND
There have been described, in EP-139,481, cosmetic compositions using, as agents for modifying the surface of inorganic compounds, for the purpose of increasing the dispersibility thereof, either an N-monoacylated derivative of a basic amino acid in which the aliphatic acyl group has from 8 to 22 carbon atoms or an N,N-diacylated derivative of a basic amino acid in which the aliphatic acyl groups, which are identical or different, having from 1 to 22 carbon atoms.
There have also been described, in EP-336,265, cosmetic compositions for hair shaping comprising, as surface-active agents, an N-monoacylated derivative of a basic amino acid in which the aliphatic acyl group has from 8 to 22 carbon atoms.
The acylated derivatives of the basic amino acids described previously are, however, very difficult and even impossible to compact.
Now, it is known that certain cosmetic, pharmaceutical and hygiene compositions are presented in the so-called “compact” form. They are anhydrous compositions consisting mainly of solid particles and of a fatty binder (oils or mixture of oils and waxes) and are shaped by compression or by pouring into a container which acts as mold.
The development of such compositions raises, however, many difficulties because the final product must be sufficiently homogeneous and compact to have a good ability to be removed and, moreover, to avoid fragmentation which may be caused, especially, by impacts.
SUMMARY OF THE INVENTION
According to the present invention, there is provided a family of compounds comprising lysine derivatives, the salts of the derivatives, as well as their optical isomers of D or L configuration, or their mixtures, the derivatives containing an N
&egr;
-alkoxy or N
&egr;
-alkenoxycarbonyl group and having a formula:
in which:
R represents a linear or branched C
8
-C
24
alkyl radical or a linear or branched C
8
-C
24
alkenyl radical.
The present invention also relates to a process for preparing these lysine derivatives and their use in cosmetic, pharmaceutical, hygiene or food compositions.
REFERENCES:
patent: 3541135 (1970-11-01), Johl et al.
patent: 4948594 (1990-08-01), Abdel-Monem et al.
patent: 5206012 (1993-04-01), Farer et al.
patent: 0139481 (1985-05-01), None
patent: 0336265 (1989-10-01), None
patent: 0447287 (1991-09-01), None
H. Gueniffey et al., “Greffage D'Acides Amines Possedant Une Troisieme Fonction Sur Un Polymere, 2”,Makromolekulare Chemie, Macromolecular Chemistry and Physics, vol. 177, Nov. 1976 pp. 3113-3118.
D. Wheeler, “Lipstick, Powder & Patents”,Soap, Perfumery & Cosmetics, vol. 65, No. 1, Jan. 1992, pp. 25-26.
Bordier Thierry
Philippe Michel
Keys Rosalynd
L'Oreal
Oliff & Berridg,e PLC
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