Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof
Patent
1999-01-22
2000-08-15
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Ammonia, amine, or derivative thereof
424 49, A61K 716, A61K 722, A61K 31195
Patent
active
061032204
ABSTRACT:
An agent, .alpha.-difluoromethyl lysine (DFML) or .alpha.-monofluoromethyl lysine (MFML), inhibits lysine decarboxylases produced by bacteria associated with periodontal tissues. Inhibition of such lysine decarboxylases can prophylactically and therapeutically treat periodontal diseases such as gingivitis and periodontitis. The agent may be incorporated into toothpastes, mouthwashes, irrigation solutions, tablets, periodontal treatment packs, or an adhesive paste or film coatings for applying to the teeth.
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