Lyophilizing and forming biologicals having a predetermined unit

Drying and gas or vapor contact with solids – Apparatus – With means to treat gas or vapor

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536 21, F26B 506

Patent

active

045219753

ABSTRACT:
A pledget of biological material of predetermined unit dosage is formed by a lyophilizing process. The lyophilizing process involves establishing a specific batch volume of sterile water, dissolving a preestablished amount of biological material in the batch volume of water, filling at least one container with a portion of the solution of water and dissolved material, and lyophilizing the solution in the container into the pledget. The amount of biological material to be dissolved in the water is established in relation to the volume and number of containers, the desired predetermined unit dosage of each pledget, and the desired number of pledgets to be formed at a time.

REFERENCES:
patent: 3199217 (1965-08-01), Oldenkamp et al.
patent: 4001944 (1977-01-01), Williams
patent: 4305502 (1981-12-01), Gregory et al.

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