Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Reexamination Certificate
2009-09-16
2010-10-05
Saoud, Christine J (Department: 1647)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
C424S192100, C514S002600, C514S012200, C530S350000, C536S023400
Reexamination Certificate
active
07807164
ABSTRACT:
Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has the amino acid sequence shown in SEQ ID NO:4.
REFERENCES:
patent: 6100071 (2000-08-01), Davis-Smyth et al.
patent: 6897294 (2005-05-01), Davis-Smyth et al.
patent: 2005/0281831 (2005-12-01), Davis-Smyth et al.
patent: 2006/0217311 (2006-09-01), Dix et al.
patent: WO 2005/000895 (2005-01-01), None
patent: WO 2006/047325 (2006-05-01), None
patent: WO 2006/104852 (2006-10-01), None
Dix Daniel
Frye Kelly
Furfine Eric
Graham Kenneth S.
Gregg, Esq. Valeta
Lockard Jon M
Regeneron Pharmaceuticals Inc.
Saoud Christine J
Smeland, Esq. Tor
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