Lyophilized preparation of platinum compound

Details Lyophilized preparation of platinum compound Lyophilized preparation of platinum compound

1988-11-22

1990-09-04

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heavy metal containing doai

A61K 3128

Patent

active

049545221

ABSTRACT:
The present invention relates to a lyophilized preparation comprising cis-1,1-cyclobutanedicarboxylate-(2R)-2-methyl-1,4-butanediamine platinum (II), which is useful as an antitumor drug, and dextran. This preparation has a greatly improved resolubility.

REFERENCES:
patent: 4310515 (1982-01-01), Granatek et al.
patent: 4315002 (1982-02-01), Maurer
patent: 4696918 (1987-09-01), Stoddart et al.
patent: 4737589 (1988-04-01), Nowatari et al.
patent: 4737589 (1988-04-01), Nowatari et al.
patent: 4767874 (1988-08-01), Shima et al.
Chemical Abstracts 107:161694u, (11/2/87).

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