Lyophilized ifosfamide compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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Details

514588, 514706, 514970, A61K 3166, A61K 3117, A61K 31095

Patent

active

052273733

ABSTRACT:
Improved lyophilizate compositions of ifosfamide comprising urea as the primary excipient and, optionally, mesna, are produced in a modified freeze-drying process to give products with increased heat stability and extended shelf storage life.

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patent: 4952575 (1990-08-01), Sauerbier et al.
patent: 4959215 (1990-09-01), Sauerbier et al.
patent: 5036060 (1991-07-01), Alam et al.

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