Lyophilized and reconstituted red blood cell compositions

Details Lyophilized and reconstituted red blood cell compositions Lyophilized and reconstituted red blood cell compositions

1989-06-29

1993-01-12

Rosen, Sam

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Blood

424529, 424450, 435 2, 514 6, A61K 3518

Patent

active

051788845

ABSTRACT:
A process and medium are disclosed for the lyophilization of red blood cells which comprises the use of solutions including monosaccharide hexoses and pentoses, and biocompatible amphipathic polymers to permit the reconstitution of viable red blood cells. Also disclosed are lyophilized and reconstituted erythrocyte and hemosome containing compositions.

REFERENCES:
patent: 3344617 (1967-10-01), Rinfret et al.
patent: 3347745 (1967-10-01), Rinfret et al.
patent: 4572899 (1986-02-01), Walker et al.
patent: 4806343 (1989-02-01), Carpenter et al.
patent: 4874690 (1989-10-01), Goodrich, Jr. et al.
Scheiwe et al., Cryobiology vol. 19, No. 5, (1982) pp. 461-477.
Green Cross Corp.--Chem. Abst. vol. 99 (1983) p. 156, 728y.
Scheiwe et al.--Chem. Abst. vol. 98 (1983) p. 14029b.

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