Lymphotoxins with antitumor activity and method for producing sa

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

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514 2, 530351, 43524021, 43524025, C12P 2100, C12N 500, A61K 3702

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active

047525754

ABSTRACT:
Two lymphotoxins are disclosed which are effective in mediating growth of malignant cell lines. The two lymphotoxins are designated as LT-2 and LT-3. A method for producing LT-2 and LT-3 is disclosed in which HUT-102 cells are stimulated with 4 Beta Phorbal 12-Myristate 13-Acetate (PMA).

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