Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of co-culturing cells
Reexamination Certificate
2007-03-20
2007-03-20
Rawlings, Stephen L. (Department: 1643)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of co-culturing cells
C435S377000, C435S382000, C435S395000, C435S399000, C435S372300
Reexamination Certificate
active
10161097
ABSTRACT:
The invention relates to a method for lymphoid tissue-specific cell production from hematopoietic progenitor cells in unique, three-dimensional culture devices, in the presence of antigen presenting cells and lymphoreticular stromal cells, and in the absence of exogenously added growth factors. The resulting lymphoid tissue-specific cells may be isolated at any sequential stage of differentiation and further expanded. The lymphoid tissue-specific cells also may be genetically altered at any stage of the process.
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Poznansky Mark C.
Pykett Mark J.
Rosenzweig Michael
Scadden David T.
Cytomatrix, LLC
Rawlings Stephen L.
Wolf Greenfield & Sacks P.C.
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