Lymphocyte chemoattractant factor

Details Lymphocyte chemoattractant factor Lymphocyte chemoattractant factor

1995-12-29

2000-12-12

Mertz, Prema

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

424 851, 514 28, 514 12, 514885, 435 6952, 435 711, 435 712, 435 713, 4352402, 4352523, 4353201, 935 11, 935 22, 935 27, 935 66, 935 70, 935 32, A61K 4500

Patent

active

061594636

ABSTRACT:
Purified DNA encoding LCF and the recombinant proteins expressed from such DNA are disclosed. In addition, the invention provides methods for suppressing an LCF-CD4 interaction and screening candidate LCF agonists or antagonists. The invention also provides compositions and methods useful for stimulating proliferation of CD4+ T-cells in a mammal.

REFERENCES:
patent: 4745051 (1988-05-01), Smith et al.
patent: 4863727 (1989-09-01), Zimmerman et al.
patent: 5965120 (1999-10-01), Center et al.
Cunningham et al. (1989) Science vol. 244, pp. 1081-1085..
George et al. (1988) Marcomolecular Sequencing & Synthesis Selected Methods & Applications. Ch. 12, pp. 127-149, Alan R. Liss, Inc, N.Y.
Rosenberg et al. (1984) Science vol. 223 pp. 1412-1415.
Maeda (1989) Ann. Rev. Entomol. vol. 34 pp. 351-372.
Berman, et al., Cellular Immunology, 95:105-112 (1985).
Berman, et al., AM Rev. Respir. Dis., 142:238-257 (1990).
Cambell, "Monoclonal Antibody Technology, The Production and Characterization of Rodent and Human Hybridomas," Elsevier Science Publishers (Amsterdam), pp. 1-4 and 29 (1984).
Center, et al., The Journal of Immunology, 128:2563-2568 (1982).
Cruikshank, et al., The Journal of Immunology, 138:3817-3823 (1987).
Cruikshank, et al., The Journal of Immunology, 146:2928-2934 (1991).
Cruikshank, et al., EMBL Database, Accession No. M90391 (1992).
Cruikshank, et al., The Journal of Immunology, 128:2569-2574 (1982).
Rand, et al., J. Exp. Med., 173:1521-1528 (1991).
Center, et al. (Feb. 1995) "The Lymphocyte Chemoattractant Factor", J. Lab. Clin. Med. 125(2) :167-172.
Cruikshank, et al. (May 24, 1994) "Molecular and Functional Analysis of a Lymphocyte Chemoattractant Factor: Association of Biologic Function with CD4 Expression", Proc. Natl. Acad. Sci. USA 91(11):5109-5113.
(May 1996) "Terminology Note: Interleukin 16 (IL-16)", Eur. J. Immunol. 26(5)1196.

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