Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1992-04-17
1994-05-31
Hill, Jr., Robert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 4352402, 4353201, 536 235, 536 2353, 536 2431, 530350, C12N 1513, C12N 1514, C12N 516
Patent
active
053169204
ABSTRACT:
Lymphocyte activation antigen HB15, and the human cDNA and gene sequences encoding HB15, are disclosed. HB15 is not expressed at detectable levels by circulating leukocytes but has a unique pattern of expression among tissues. HB15 is uniquely expressed by Langerhans cells within the skin and other subpopulations of dendritic cells. Also disclosed are antibodies reactive with HB15 and methods of using anti-HB15 antibodies, or other antagonists to HB15 function, to treat an immunological disorder, disease or syndrome.
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Tedder Thomas F.
Zhou Liang-Ji
Dana-Faber Cancer Institute, Inc.
Fitzgerald David L.
Hill Jr. Robert J.
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