Lung surfactant compositions

Details Lung surfactant compositions Lung surfactant compositions

1986-11-05

1989-05-02

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

A61K 31685

Patent

active

048268216

ABSTRACT:
An improved synthetic lung surfactant consists essentially of dipalmitoyl phosphatidyl choline, a C-14 to C-18 fatty alcohol (preferably hexadecanol), and a non-toxic nonionic surface active agent (preferably tyloxapol). The surfactant is prepared in a powdered lyophilized form that can be stored for extended periods at room temperature. The powdered product can be readily reconstituted by simply adding distilled water.

REFERENCES:
patent: 4312860 (1982-01-01), Clements
Chemical Abstracts, vol. 86 (1977), #66212c; Soler-Argilaga et al.
Chemical Abstracts, vol. 85 (1976), #187244c; Melin et al.
Science, vol. 111 (1950), pp. 688 and 689, Glassman.

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