Luminous compounds and labeling reagents using the same

Details Luminous compounds and labeling reagents using the same Luminous compounds and labeling reagents using the same

2006-12-26

2006-12-26

Witherspoon, Sikarl A. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfur containing

C568S331000, C568S336000, C564S143000, C564S155000, C564S308000, C436S501000

Reexamination Certificate

active

07154007

ABSTRACT:
This invention provides: a compound represented by formula (I):in-line-formulae description="In-line Formulae" end="lead"?R—Y—(—X-Phe-COCH2COCnF2n+1)m  (I)in-line-formulae description="In-line Formulae" end="tail"?wherein R denotes hydrogen, alkyl, phenyl, or a group capable of binding to a protein, peptide, amino acid, nucleic acid, or nucleotide; Y denotes CH2, a carbocyclic ring, or a heterocyclic ring; X denotes O, S, NH, CH2, OCH2, CONH, or NHCO; Phe denotes phenylene; n is an integer between 1 and 5; and m is 1, 2, or 3. This inventions also provides a luminous complex of such compound and a rare earth ion, a labeling reagent comprising such compound or luminous complex, and a process for labeling a protein, peptide, amino acid, nucleic acid, or nucleotide using such labeling reagent.

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