Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Reexamination Certificate
2008-03-04
2008-03-04
Gitomer, Ralph (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
C435S029000, C435S032000, C435S069100
Reexamination Certificate
active
07338778
ABSTRACT:
The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensitivity of the luminescent emission of certain compounds to the presence of oxygen, which quenches (diminishes) the compound's luminescent emission in a concentration dependent manner. Respiring eukaryotic and/or prokaryotic cells will affect the oxygen concentration of a liquid medium in which they are immersed. Thus, this invention provides a convenient system to gather information on the presence, identification, quantification and cytotoxic activity of eukaryotic and/or prokaryotic cells by determining their effect on the oxygen concentration of the media in which they are present.
REFERENCES:
patent: 5030420 (1991-07-01), Bacon et al.
patent: 5164796 (1992-11-01), Di Guiseppi et al.
patent: 5511547 (1996-04-01), Markle et al.
patent: 5567598 (1996-10-01), Stitt et al.
patent: 6063617 (2000-05-01), Young et al.
patent: 6107083 (2000-08-01), Collins et al.
patent: 6190612 (2001-02-01), Berger et al.
patent: 6254829 (2001-07-01), Hartmann et al.
patent: 6395506 (2002-05-01), Pitner et al.
patent: 6565992 (2003-05-01), Manners et al.
patent: 6711423 (2004-03-01), Colvin, Jr.
patent: 6900030 (2005-05-01), Pitner et al.
patent: 6967086 (2005-11-01), Guarino et al.
patent: 2004/0106209 (2004-06-01), Keith
Beaty Patrick Shawn
Burrell Gregory J.
Foley, Jr. Timothy G.
Guarino Richard D.
Hemperly John Jacob
Becton Dickinson and Company
Gitomer Ralph
LandOfFree
Luminescent method for determining cell oxygen consumption does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Luminescent method for determining cell oxygen consumption, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Luminescent method for determining cell oxygen consumption will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2807646