Luminescent labelling materials and procedures

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C546S104000, C546S107000

Reexamination Certificate

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07122671

ABSTRACT:
A compound for use as a chemiluminescent label in immunoassay comprises an aryl acridinium ester linked to an N-succinimidyl moiety. The compound is conveniently linked to a monoclonal antibody or other protein and is used in a two-site immunoassay for the quantitation of an antigen of interest, by initiation of the luminescent reaction and subsequent measurement of the photonic emission of the immune complex formed during the immunological reaction.

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patent: 0 216 553 (1987-01-01), None
McCapra Acct. of Chem Res, vol. 9, No. 5, pp. 201-208, 1976.
Weeks et al Clin. Chem vol. 29, No. 8, pp. 474-479, 1983.

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