Luminescent conjugates for use in luminescent assays

Chemistry: analytical and immunological testing – Tracers or tags

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4284022, 42840221, 42840222, G01N 33533

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active

056565003

ABSTRACT:
Vesicular luminescent conjugates comprising liposomes coupled to molecules with biological activity, such as antigens, antibodies, and nucleic acids, for use in luminescent assays, are described herein. These conjugates encapsulate hydrophilic polysubstituted aryl acridinium esters and are useful as chemiluminescent tracers in immunoassays and other binding assays.

REFERENCES:
patent: 3352791 (1967-11-01), Sheehan et al.
patent: 3689391 (1972-09-01), Ullman
patent: 4098876 (1978-07-01), Piasio et al.
patent: 4193983 (1980-03-01), Ullman et al.
patent: 4244940 (1981-01-01), Jeong et al.
patent: 4656129 (1987-04-01), Wagner
patent: 4695554 (1987-09-01), O'Connell et al.
patent: 4704355 (1987-11-01), Bernstein
patent: 4745181 (1988-05-01), Law et al.
patent: 4918192 (1990-04-01), Law et al.
patent: 4933121 (1990-06-01), Law et al.
patent: 4946958 (1990-08-01), Campbell et al.
patent: 4950613 (1990-08-01), Arnold et al.
patent: 4978614 (1990-12-01), Bronstein
patent: 5004565 (1991-04-01), Schaap
patent: 5094785 (1992-03-01), Law et al.
patent: 5110932 (1992-05-01), Law et al.
patent: 5281712 (1994-01-01), McCapra et al.
Allen et al., 247 J. Biol Chem 7695 (1972).
Anderson et al., B33 Acta Chemica Scandinavia 695 (1979).
Applied Biosystems, Inc., Foster City, CA, User Manual for DNA/RNA Synthesizer, (1990), iii-vii, 6-1 to 6-21.
Applied Biosystems, Inc., Peptide Synthesizer User's Manual (1988), pp. 0-4 to 0-11, 6-5 to 6-18.
Clontech Laboratories, Inc., Palo Alto, CA, User Manual on DNA Modification Reagents for Use in Automated DNA Synthesis, p. 2-3.
Hammond et al., 6 J. Biolum and Chemilum., 35-43 (1991).
Hendrickson et al., Organic Chemistry, 3d. ed., McGraw Hill, NY (1970), p. 71.
Kricka, L. and Carter T., Clinical and Biochemical Luminescence, pp. 153-178 (Marcel Dekker, Inc., NY. and Basel, 1982).
March, Advanced Organic Chemistry, 3d. ed., John Wiley & Sons, NY (1985), p. 304-310, 587.
Martinet et al., Bull Soc Chim Fr., vol 45 pp. 101-109 (1929).
Mayer et al., "Hydrophilic Acridinium-9-Carboxylic Acid Derivatives Used as Labels in Luminescent Assays" in Stanley et al. Eds., p. 99 (1991, Wiley, Chichester).
Meek et al., 11 J. Chem & Eng Data, vol 14, p. 388-391 (1969).
Miller et al., 25 Ann Clin Biochem 27-34 (1988).
Patel et al., 97 CA 85407p (1982).
Richardson et al., 31/10 Clin Chem 1664-8 (1985).
Weeks et al., 29 Clin Chem 1474 (1983).

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