Luminescence indicator including ionophoric moiety

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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540469, 540472, 548110, 548405, 544229, 544106, 544336, C07D41902, C07D20956

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active

060019999

ABSTRACT:
The invention relates to a compound having the general Formula I in which one of the groups R.sub.1,R.sub.2,R.sub.3,R.sub.4,R.sub.5,R.sub.6 and R.sub.7 represents an ionophoric moiety and the remaining groups each independently are hydrogen, a lipophilic or hydrophilic group or a reactive group for coupling to a polymer or a biomolecule, or R.sub.2 forms an aromatic ring system together with R.sub.3 and R.sub.5 forms an aromatic ring system together with R.sub.6.
the compound of the invention is useful as a luminescence indicator for cations.

REFERENCES:
patent: 4774339 (1988-09-01), Haugland et al.
patent: 5162525 (1992-11-01), Masilamani et al.
patent: 5187288 (1993-02-01), Kang et al.
patent: 5248782 (1993-09-01), Haugland et al.
patent: 5274113 (1993-12-01), Kang et al.
patent: 5433896 (1995-07-01), Kang et al.
patent: 5439828 (1995-08-01), Masilamani et al.
patent: 5451663 (1995-09-01), Kang et al.
patent: 5516911 (1996-05-01), London et al.
R. Crossley, et al., "Synthesis and Properties of a Potential Extracellular Fluorescent Probe for Potassium", J. Chem. Soc. Perkin Trans. 2, pp. 1615-1622 (1994).
M.R. Angelastro et al., J. Med. Chem. vol. 37, pp. 4538-4553 (1994).
J.R. Lakowicz, "Topics in Fluorescence Spectroscopy", vol. 4: Probe Design and Chemical Sensing, pp. 133-134 (Plenum Press, New York & London) (1994).
Frank Kastenholz, Inaugural Dissertation, University of Cologne, Fig. 32, p. 54 (1993).
M.J.P. Leiner, P. Hartmann, "Theory and Practice in optical pH sensing", Sensors and Actuators B, 11, pp. 281-289 (1993).
H. Wang, D.D. Weller, "Solid Phase Synthesis of Neutral Oligonucleotide Analogues",Tetrahedron Letters, vol. 32, No. 50, pp. 7385-7388 (1991).
A.P. de Silva et al., "A New Benzo-Annelated Cryptand and a Derivative with Alkali Cation-Sensitive Fluorescence", Tetrahedron Letters, vol. 31, No. 36, pp. 5193-5196 (1990).
B. Dietrich, et al., Tetrahedron vol. 29, pp. 1629-1645 (1973).
W.O. Foye, L.R. Fedor, Jr., "The Preparation of Oxidized Derivatives of 1-Ethylsulfonyl-4-ethylpiperazine", Journal of the American Pharmaceutical Association, vol. 48, No. 7, pp. 412-414 (1959).
CA 99:177723h. (1983).

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