Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Patent
1998-04-28
2000-05-02
McKane, Elizabeth
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
422 8208, G01N 2176
Patent
active
060571632
ABSTRACT:
A sample reading apparatus and method. The apparatus includes a detection system for reading samples, a sample carrier support for holding a sample carrier in position for reading by the detection system, and a mask configured to expose selected portions of the sample carrier while covering other portions of the sample carrier such that the detection system reads the exposed portions of the sample carrier. At least one of the sample carrier and mask are movable to expose different portions of the sample carrier while covering other portions of the sample carrier. The method includes positioning a sample carrier on a support, obstructing a surface of the sample carrier with a mask which exposes selected portions of the sample carrier while covering other portions of the sample carrier, activating a detection system to read the contents of the portions of the sample carrier exposed by the mask, producing relative motion of the sample carrier and the mask to expose different portions of the sample carrier while covering other portions of the sample carrier including the previously exposed portions of the sample carrier, and activating a detection system to read the contents of the different portions of the sample carrier exposed by the mask.
REFERENCES:
patent: 4710031 (1987-12-01), Kelly et al.
patent: 4922092 (1990-05-01), Rushbrooke et al.
patent: 5048957 (1991-09-01), Berthold et al.
patent: 5202091 (1993-04-01), Lisenbee
patent: 5290513 (1994-03-01), Berthold et al.
patent: 5294795 (1994-03-01), Lehtinen et al.
patent: 5298753 (1994-03-01), Sonne et al.
patent: 5306914 (1994-04-01), Yrjonen et al.
patent: 5329123 (1994-07-01), Oikari et al.
patent: 5342581 (1994-08-01), Sanadi
patent: 5401465 (1995-03-01), Smethers et al.
patent: 5610883 (1997-03-01), Yanagawa
patent: 5611994 (1997-03-01), Bailey et al.
Gerard N. Skews, "Advanced Imaging Analyzes Electrophoresis Gels", Biophotonics International, Electrophoresis Imaging, Sep./Oct. 1997 pp. 46-49.
P.H. Jago, et al., "An Evaluation of the Performance of Ten Commercial Luminometers", Journal of Bioluminescence and Chemiluminescence, vol. 3, Apr. 1989, pp. 131-145.
Haggart, R. et al., "The Photometric Properties of Cooled Slow-Scan Charge Coupled Devices as Detectors in Systems for Luminogenic Assays", Journal of Bioluminescence and Chemiluminescence (1990), pp. 365-368.
Hooper, Claire E., et al., "Quantitative Photon Imaging in the Life Sciences Using Intensified CCD Cameras", Journal of Bioluminescence and Chemiluminescence (1990), pp. 337-344.
Brauer, Reinhard, et al., "Measuring Luminescence with a Low Light-Level Imaging System Using Electronic Light Standards", Journal of Bioluminescence and Chemiluminescence (1993), pp. 13-17.
Hooper, C.E., et al., "Measurement and Analysis of Chemiluminescent Protein and DNA Blots Using Photon Imaging with an Intensified CCD Camera", Journal of Bioluminescence and Chemiluminescence (1993), pp. 23-27.
Alton, G., et al., "Evaluation of a Versatile Imaging Camera Apparatus for Chemiluminescent ELISA and Monitoring Bacterial Bioluminescence", Journal of Bioluminescence and Chemiluminescence (1993), pp. 3-7.
Rushbrooke, J.G., et al., Luminescence Imaging in the Life Sciences Using an Intensified CCD System, Journal of Bioluminescence and Chemiluminescence (1993), pp. 28-32.
Wick, Robert A., et al., "A Comparison of Cooled CCD and Intensified CCD Detectors for luminescence Imaging", Journal of Bioluminescence and Chemiluminescence (1993), pp. 47-51.
Bernroider, G., et al., "Imaging Receptor Binding by Luminescence", Journal of Bioluminescence and Chemiluminescence (1993), pp. 8-12.
Berthold, F., et al., "An Imaging System for Bio-and Chemiluminescence, Fluorescence, ad Radioactivity", Journal of Bioluminescence and Chemiluminescence (1994), pp. 617-620.
Schoenfelner, B., et al., "The Lumigen CCD Camera System: An Economical Cooled CCD Camera System for Chemiluminescent Applications", Journal of Bioluminescence and Chemiluminescence (1994), pp. 633-636.
Mayerhofer, R., et al., "Visualization of Light Emission from Different Luciferases in Transgenic Organisms", Journal of Bioluminescence and Chemiluminescence (1994), pp. 607-611.
Ingle, M., et al., "Photon Counting Systems for Bioluminescence Imaging", Journal of Bioluminescence and Chemiluminescence (1994), pp. 637-640.
Fullam, PS, et al., "Comparison of Real Life Luminometer Sensitivity as Determined with Actual Luminescence Assays", Journal of Bioluminescence and Chemiluminescence (1996 pp. 553-556.
Mockel, B., et al., "The Night Owl Molecular Light Imager--a Low-Light Imaging System for Bio-and Chemiluminescence and Fluorescence", Journal of Bioluminescence and Chemiluminescence (1996), pp. 539-542.
Gutekunst, M., et al., The Lumi-Imager.TM., a Sensitive and Versatile System for Imaging, Analysis and Quantitation of Chemiluminescence on Blots and in Microtiterplates, Journal of Bioluminescence and Chemiluminescence (1996), pp. 543-544.
Contag, Christopher H., et al., "Visualizing Gene Expression in Living Mammals Using a Bioluminescent Reporter", Photochemistry and Photobiology , 1997, 66(4), pp. 523-531.
Astromed Limited Brochure, "Astromed Ultra low light level imaging systems", Astromed Limited, Cambridge, England.
EG&G Berthold Brochure, "Luminograph LB 980", EG&G Berthold, Bad Wildbad, Germany.
Hamamatsu Brochure, "ARGUS-50 Series", Hamamatsu Photonics, Hamamatsu, Japan.
Image Research Brochure, "BIQ The Biomedical Image Quantifier", Image Research, Cambridge, England.
McKane Elizabeth
McNeil Jennifer
Turner Designs
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