Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...
Patent
1995-03-29
1998-12-22
Schwadron, Ronald B.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Animal cell, per se, expressing immunoglobulin, antibody, or...
435346, 436548, 53038822, 5303882, 5303891, 530809, 935 89, 935 95, 935104, C07K 1618, C07K 1628, C12N 520, C12N 518
Patent
active
058518304
ABSTRACT:
A cell-surface glycoprotein, termed luminal epithelial antigen, having a molecular weight of 135 Kd and which is present in normal mammary epithelial cell lines but not in malignant epithelial cell lines. A monoclonal antibody directed against said luminal epithelial antigen. Use of the monoclonal antibody in a diagnostic assay for the early identification of patients with high risk of developing breast cancer and in a prognostic assay for the prediction of recurrence of breast cancer in patients.
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Imam S. Ashraf
Taylor Clive R.
Schwadron Ronald B.
University of Southern California
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