Luliberin analogs

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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2601125LH, A61K 3700, C07C10352

Patent

active

041247035

ABSTRACT:
The disclosure relates to novel polypeptides which are analogues of luliberin and which possess luliberin antagonist activity, to processes for their manufacture and to compositions containing them. Typical of the polypeptides disclosed is ##STR1## in which A is D-Phe, D-Trp or a direct bond.

REFERENCES:
patent: 3928307 (1975-12-01), Foell et al.
A. S. Dutta, et al., Clinical Endocrinology (1976) pp. 291S-298S.

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