Lubricious ophthalmic solutions

Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Aftertreated solid synthetic organic polymer

Reexamination Certificate

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Details

C424S427000, C424S659000, C514S772000

Reexamination Certificate

active

07022740

ABSTRACT:
There are provided lubricious ophthalmic solutions having a pH of between about 7.0 and about 8.0, consisting essentially of an aqueous solution of from about 0.5–4% by weight of a monographed polyol, borate calculated as the borate equivalent of 20–100% by weight of boric acid relative to said polyol, from about 0.1 to about 1.00% by weight of monographed polysorbate, a monographed preservative and a buffer. Suitably the polyol is polyvinyl alcohol In addition to polyvinyl alcohol (hereinafter PVA) the solution may include other monographed polymers as well as monographed pharmacologically active substances.

REFERENCES:
patent: 3697575 (1972-10-01), Naarmann
patent: 4066541 (1978-01-01), Sando
patent: 4331781 (1982-05-01), Zimmerman
patent: 5234968 (1993-08-01), Debus
patent: 5290774 (1994-03-01), Morita
patent: 5342620 (1994-08-01), Chowhan
patent: 5505953 (1996-04-01), Chowhan
patent: 5597559 (1997-01-01), Olejnik
patent: 6319464 (2001-11-01), Asgharian
patent: 6583124 (2003-06-01), Asgharian
patent: 1101364 (1995-04-01), None
patent: 54150468 (1979-11-01), None
patent: 12368866 (1986-10-01), None
patent: WO 9318764 (1993-09-01), None

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