Lubricants for use in tabletting

Details Lubricants for use in tabletting Lubricants for use in tabletting

1997-09-30

1998-12-01

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 424489, 424464, A61K 946, A61K 920

Patent

active

058434771

ABSTRACT:
The invention provides a new water soluble lubricant combination which facilitates the production of tablets. The combination of glyceryl behenate and fumaric acid is useful as a lubricant, particularly in tablet compositions containing ingredients where rapid dissolution in an aqueous environment is desired for activity or desired for aesthetic purposes. This lubricant combination has fewer limitations and improved functionality in comparison to standard lubricants presently known. In addition, the lubricants provided may be used with known hydrophobic lubricants to decrease the amount of the hydrophobic lubricant required for lubrication.

REFERENCES:
patent: 4783331 (1988-11-01), Alexander et al.
patent: 4965072 (1990-10-01), Alexander et al.
patent: 5445827 (1995-08-01), Fritsch et al.
patent: 5587179 (1996-12-01), Gergely et al.
patent: 5639475 (1997-06-01), Bettman et al.
patent: 5650169 (1997-07-01), Conte et al.
patent: 5681583 (1997-10-01), Conte et al.
patent: 5709886 (1998-01-01), Bettman et al.
patent: 5728401 (1998-03-01), Ahmed et al.

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