Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-10-27
1993-06-08
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546293, 546298, 546305, 546312, 546315, 546326, 546276, 514346, 514348, 514349, 514350, 514352, 514353, 514354, 514355, 514356, A61K 3144, C07D21172, C07D21184
Patent
active
052179818
ABSTRACT:
This invention relates to a compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, --CH.dbd.CH--or --CH.dbd.N--; wherein R.sub.1 is alkyl, alkenyl or alkynyl of about 1 to 20 carbon atoms; wherein R is --CO.sub.2 R.sup.2, tetrazole, methylsulfonamide or benzenesulfonamide, wherein R.sup.2 is hydrogen, alkyl of 1 to 6 carbon atoms or a pharmaceutically acceptable cation and R.sup.3 is hydroxyl or halogen, having utility as LTB.sub.4 synthesis inhibitors.
REFERENCES:
patent: 3255241 (1966-06-01), Schultz et al.
patent: 3912656 (1975-10-01), Andrews et al.
patent: 3919250 (1975-11-01), Pauling
Chem. Abstracts; McCarthy et al. 117, (5), 48340x (1991).
Djuric Stevan W.
Haack Richard A.
Miyashiro Julie M.
G. D. Searle & Co.
Matukaitis Paul D.
Richter Johann
Williams Roger A.
LandOfFree
LTB4 synthesis inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with LTB4 synthesis inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and LTB4 synthesis inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1934283