Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-11-04
1992-08-04
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
564 91, 514602, 548252, 548253, A61K 3141, A61K 3118, C07C30300, C07D25700
Patent
active
051359413
ABSTRACT:
This invention relates to a compound of the formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, --CH.dbd.CH-- or --CH.dbd.N--; wherein R.sub.1 is alkyl, alkenyl or alkynyl of about 1 to 20 carbon atoms; wherein R is --CO.sub.2 R.sup.2, tetrazole, methylsulfonamide or benzenesulfonamide, wherein R.sup.2 is hydrogen, alkyl of 1 to 6 carbon atoms or a pharmaceutically acceptable cation and R.sup.3 is hydroxyl or halogen, having utility as LTB.sub.4 synthesis inhibitors.
REFERENCES:
patent: 3917692 (1975-11-01), Grunwald
Djuric Stevan W.
Haack Richard A.
Miyashiro Julie M.
G. D. Searle & Co.
Matukaitis Paul D.
Morris Patricia L.
Whittenbaugh Robert C.
Williams Roger A.
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