Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-03-12
1999-07-20
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514422, 514423, 514427, 514428, 514429, 546213, 548518, 548531, 548537, 548561, 548565, C07D20708, C07D207325, A61K 3140
Patent
active
059256540
ABSTRACT:
The present invention provides compounds having the structure: ##STR1## and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
REFERENCES:
patent: 5700816 (1997-12-01), Isakson et al.
Chem. Abstracts, vol. 117(11), Abstr. No. 111411, Sep. 14, 1992.
Yuan et al., Chem. Abstracts, vol. 126(1), Abstr. No. 302, Jan.1, 1997.
Cavallini et al., Chem. Abstracts, vol. 53(10), Abstr. No. 9194, May 25, 1959.
Labaudiniere, R. et al., J. Med. Chem., vol. 35 (17), pp. 3156-3169 (1992).
Chen Barbara Baosheng
Chen Helen
Malecha James
Miyashiro Julie Marion
Penning Thomas Dale
G.D. Searle & Co.
Rao Deepak R.
Shah Mukund J.
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