LTA.sub.4 hydrolase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514444, 514445, 514447, 514604, 514605, 514365, 514369, 514370, 514342, 514255, 549 59, 549 68, 549 77, 564 91, 564 99, 548187, 548195, 548198, 548204, 5462804, A61K 3138, A61K 3118, C07D33322, C07C30300

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active

061628239

ABSTRACT:
The present invention provides compounds having the of the formula I: ##STR1## and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.

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Chem. Abstracts, vol. 126(1), Abstr. No. 302, Jan. 1, 1997.
Chem. Abstracts, vol. 53(10), Abstr. No. 9194, May 25, 1959.

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