Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-03-12
2000-12-19
Lambkin, Deborah C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514444, 514445, 514447, 514604, 514605, 514365, 514369, 514370, 514342, 514255, 549 59, 549 68, 549 77, 564 91, 564 99, 548187, 548195, 548198, 548204, 5462804, A61K 3138, A61K 3118, C07D33322, C07C30300
Patent
active
061628239
ABSTRACT:
The present invention provides compounds having the of the formula I: ##STR1## and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
REFERENCES:
patent: 6046229 (2000-04-01), Chang et al.
patent: 6051599 (2000-04-01), Elliot et al.
patent: 6063928 (2000-05-01), Stevens et al.
Labaudiniere, R. et al., J. Med. Chem., vol. 35 (17), pp. 3156-3169 (1992).
Yuan, J.H. et al., Drug Metab. Dispos., vol. 24(10), pp. 1124-1133 (1996).
Cavallini V.G. et al., Farmaco Ed. Sci., vol. 11, pp. 378-388 (1956).
Chem. Abstracts, vol. 117(11), Abstr. No. 111411, Sep. 14, 1992.
Chem. Abstracts, vol. 126(1), Abstr. No. 302, Jan. 1, 1997.
Chem. Abstracts, vol. 53(10), Abstr. No. 9194, May 25, 1959.
Liang Chi-Dean
Malecha James
Penning Thomas Dale
Russell Mark Andrew
Yu Stella Siu-tzyy
G.D. Searle & Co.
Lambkin Deborah C.
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