LRF Antagonists

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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2601125LH, A61K 3700, C07C10352

Patent

active

043070833

ABSTRACT:
Peptides which inhibit the secretion of gonadotropins by the pituitary gland and inhibit the release of steroids by the gonads. Administration of an effective amount prevents ovulation of female mammalian eggs and/or the release of steroids by the gonads. The peptides have the structure:

REFERENCES:
patent: 3928307 (1975-12-01), Foell et al.
patent: 3933782 (1976-01-01), Yardley
patent: 4010125 (1977-03-01), Schally et al.
patent: 4072668 (1978-02-01), Amoss et al.
patent: 4075191 (1978-02-01), Beddell et al.
patent: 4124703 (1978-11-01), Dutta et al.
patent: 4128638 (1978-12-01), Moody
patent: 4215038 (1980-07-01), Rivier et al.
J. Rivier et al., "Peptides", 1976, pp. 427-451.

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