Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1996-05-17
1999-09-14
Knode, Marian C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514889, 53612313, A61K 3170, C07H 304
Patent
active
059523131
ABSTRACT:
Compositions for antagonizing gram negative bacterial endotoxic activity. Methods of antagonizing gram negative bacterial endotoxic activity. Methods of treating septic or toxic shock in a patient. Methods of treating or preventing a lipopolysaccharide mediated disorder in a patient. A method of extracting lipopolysaccharide from a gram negative bacteria by releasing lipopolysaccharide from a gram-negative bacteria, contacting the released lipopolysaccharide with polymixin B-agarose, and eluting the lipopolysaccharide from the polymixin B-agarose with an eluting solution comprising at least 1% deoxycholate to obtain thereby an lipopolysaccharide product.
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Knode Marian C.
Lee Howard C
University of Georgia Research Foundation Inc.
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