Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Reexamination Certificate
2007-05-15
2007-05-15
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
C558S213000, C514S094000, C514S119000, C548S342100, C548S351100
Reexamination Certificate
active
10963085
ABSTRACT:
The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, treating a wound, treating apoptosis or preserving or restoring function in a cell, tissue, or organ, culturing cells, preserving organ or tissue function, and treating a dermatological condition.
REFERENCES:
patent: 1085074 (2001-03-01), None
Muller, et al. “Nuclear Magnetic resonance spectra of phosphorus compounds” J. Amer. Chem. Soc., vol. 78, 3557-3561 (1956).
Pellerite et al., “Effects of Fluorination on Self-Assembled Monolayer Formation from Alkanephosphonic Acids on Aluminum: Kinetics and Structure,”J. Phys. Chem. B107:11726-11736 (2003).
Durgam Gangadhar G.
Miller Duane D.
Tigyi Gabor
Tsukahara Ryoko
Virag Tamas
Grazier Nyeemah
McKane Joseph K.
The University of Tennessee Research Foundation
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