Lozenge or chewable tablet

Details Lozenge or chewable tablet Lozenge or chewable tablet

1992-07-01

1994-05-17

Phelan, Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

424 44, 424 48, 424466, 424481, 424686, A61K 928

Patent

active

053126262

ABSTRACT:
The lozenge or chewable tablet contains, as the base, at least 30, preferably 50 to 70, percent by weight of an alkali metal and/or alkaline earth metal salt of at least one edible, organic acid, at least 10, preferably 20 to 40, percent by weight of a mixture of at least one unreacted, edible organic acid with at least one unreacted alkali metal or alkaline earth metal carbonate and/or bicarbonate and, if required, a pharmaceutical active substance and/or other conventional tablet assistants, such as flavors and sweeteners, disintegrants, hydrocolloids, etc. It contains essentially the dibasic alkali metal and/or alkaline earth metal salt of a tribasic, edible, organic acid, in particular of citric acid, and preferably an edible, organic acid, which in particular has reacted only partially to give the alkali metal and/or alkaline earth metal salt, in particular malic acid, which is stronger than the tribasic acid, and if required--based on the total tablet weight--1 to 10, preferably 3 to 7, percent by weight of at least one disintegrant, in particular about 3 percent by weight each of starch and crosslinked polyvinylpyrrolidone.

REFERENCES:
patent: 4650669 (1987-03-01), Alexander
patent: 4664915 (1987-05-01), Simonian
patent: 4762702 (1988-08-01), Gergely
patent: 4867942 (1989-09-01), Gergely
patent: 4867989 (1989-09-01), Silva
patent: 5037657 (1991-08-01), Jones
patent: 5096714 (1992-03-01), Kuhrts

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