Lowering lipid and sugar levels in the blood with a bis(4-hydrox

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260473S, 260520R, 260559D, 424317, 424359, 424360, 424361, 424363, A61K 3119, A61K 31215

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active

040072827

ABSTRACT:
Pharmaceutical compositions acting on the metabolism which contain as active substance bis(4-hydroxy-phenyl)alkanoic acids corresponding to the formulae I and II ##STR1## wherein R.sup.1 and R.sup.2 wich may be identical or different, each stands for a hydrogen or halogen atom or an alkyl group having 1 to 4 carbon atoms, R.sup.3 stands for a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, R.sup.4 stands for hydroxy, alkoxy having 1 to 18 carbon atoms, phenyl-alkoxy having 1 to 4 alkyl carbon atoms, cycloalkoxy having 5 to 8 carbon atoms or a group of the formula ##STR2## in which Z and Z', which may be identical or different, each stands for hydrogen, alkyl of 1 to 18 carbon atoms, phenyl or cycloalkyl of 5 to 8 carbon atoms, or both together with the nitrogen atom may form a heterocyclic ring, R.sup.6 stands for an alkylene radical having 2 to 12 atoms and n stands for zero or an integer of 1 to 6, and process for preparing them.

REFERENCES:
patent: 2933520 (1960-04-01), Bader
patent: 3043746 (1962-07-01), Cavallini et al.
patent: 3471537 (1969-10-01), Berke et al.
patent: 3471554 (1969-10-01), Holmen
patent: 3499008 (1970-03-01), Falet et al.
patent: 3514472 (1970-05-01), Berke et al.

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