Low-substrate-specific amino acid racemase and process for...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Isomerase

Reexamination Certificate

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C435S252330, C435S252340, C435S320100, C435S252300, C435S325000, C435S069100, C536S023200

Reexamination Certificate

active

07666653

ABSTRACT:
The present invention provides a protein having low-substrate-specific amino acid racemase activity; DNA encoding the protein; a recombinant DNA comprising the DNA; a transformant carrying the recombinant DNA; a process for producing the protein by using the transformant; and a process for producing a racemic amino acid which comprises allowing a culture of the transformant or a treated matter thereof as an enzyme source and an amino acid to be present in an aqueous medium to racemize the amino acid in the aqueous medium, and recovering the racemic amino acid from the aqueous medium.

REFERENCES:
patent: 57-83288 (1982-05-01), None
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T. Nakamura, et al., “Racemization of Cysteine and Selenocysteine by Low-substrate-specific Amino Acid Racemase”, Sulfur Amino Acids, 1984, vol. 7, No. 2, pp. 443-447, Aug. 25, 1984, with English Abstract.
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Supplementary European Search Report, dated Feb. 17, 2006, for Application No. EP 03 74 3525.
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U. Strych, et al., “Characterizatoin of the Alanine Racemases fromPseudomonas aeruginosaPAO1”,Current Microbiology, vol. 41, No. 4, pp. 290-294, 2000 (XP-002364661); sequence listing, 2 pp. (XP-002364620); andEuropean Bioinformatics Institute, Alignment Display, (sequence listing), 2 pp.
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