Low sodium peritoneal dialysis solution

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Alkali or alkaline earth chloride

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424679, 424680, 424681, 424686, 424717, 514 2, 514 23, 514557, A61K 3800, A61K 3310, A61K 3314, A61K 3170

Patent

active

056310250

ABSTRACT:
An improved peritoneal dialysis solution and methods of administering same to a patient are provided. Pursuant to the present invention, the sodium concentration in the solution is decreased thus causing sodium to be transported from the circulation to the peritoneal cavity. This provides for an improved ultrafiltration profile for the same initial osmolality when compared to standard solutions. Also, the same ultrafiltration profile as standard solutions can be achieved with lower initial osmolalities.

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patent: 5091094 (1992-02-01), Veech
patent: 5211643 (1993-05-01), Reinhardt et al.
Nakayama, Studies on the Sodium Concentration of Dialysate for Continuous Ambulatory Peritoneal Dialysis, Japanese Journal of Nephrology, 34(8):913-20 (Aug. 1992).
Nakayama, Clinical Effect of Low Na Concentration Dialysate (120 mEq/L) for CAPD Patients, PD Conference, San Diego, CA (Mar. 1993).

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