Low pH pharmacologically active products and methods for the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

Reexamination Certificate

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C514S159000, C514S474000, C514S560000, C514S769000

Reexamination Certificate

active

07741366

ABSTRACT:
There is provided a new technology that will allow the formulation of pharmaceutically active organic acid products at relatively high pH during storage. This affords the advantages of avoiding formulation with the acid form of the product, yet when the product is used, the pH will be reduced via a chemical reaction, thus forming the organic acid which is the active form of the product. A by-product of the reaction is a significant increase in temperature, thus adding to the efficacy of the organic acid.

REFERENCES:
patent: 6120756 (2000-09-01), Markowitz
patent: 2004/0062735 (2004-04-01), Sun et al.
STN online, file BIOSIS, Acc. No. 1945:10947, Doc. No. PREV19451900011002 (Keeney et al., Bull. Johns Hopkins Hosp. (1994), vol. 75, No. 6, pp. 377-392), Abstract.

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