Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-04-20
1997-06-24
Feisee, Lila
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530413, 435803, 4351723, 4352523, 43525233, C07K 116
Patent
active
056418701
ABSTRACT:
A process for purifying an antibody is provided. In this process, a mixture containing the antibody and contaminant is subjected to low pH hydrophobic interaction chromatography (LPHIC) optionally at low salt concentration. The antibody is eluted from the column in the fraction which does not bind thereto. This process can be preceded and followed by other purification steps.
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Rinderknecht Ernst H.
Zapata Gerardo A.
Feisee Lila
Genentech Inc.
Lee Wendy M.
Reeves Julie E.
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