Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-05-01
1998-12-01
Carlson, Karen Cochrane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530385, 435 691, C07K 14805, C07H 2106
Patent
active
058438882
ABSTRACT:
A non-naturally occurring mutant hemoglobin (.alpha.96Val.fwdarw.Trp) is provided that has a lower oxygen affinity than that of native hemoglobin, but high cooperativity in oxygen binding. The mutant hemoglobin is preferably obtained by recombinant DNA techniques. Such a mutant hemoglobin may be used as a component of a blood substitute.
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Ho Chien
Kim Hyun-Won
Shen Tong-Jian
Carlson Karen Cochrane
Carnegie Mellon University
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