Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1992-09-29
1993-12-21
Hollrah, Glennon A.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
436173, 1286534, 534 16, 536 20, 536 552, 514 54, 514 55, 514 62, 514836, G01N 2408, A61K 31715, C08B 3708
Patent
active
052719243
ABSTRACT:
There is disclosed an imaging agent for diagnosis comprising a compound composed of a polynuclear type compound of the formula I or II: ##STR1## wherein each X is a hydrogen atom or a bifunctional ligand, at least one of them are bifunctional ligand and m or n is an integer of 1 to 6, and at least one metal ion being coordinated with at least one bifunctional ligand moiety, said metal ion being selected from the group consisting of metal ions having the atomic number of 21-29, 31, 32, 37-39, 42-44, 49 and 56-83.
REFERENCES:
patent: 5141739 (1992-08-01), Jung et al.
patent: 5143716 (1992-09-01), Unger
Gibby, Wa et al. Invest. Radiol. 24:302-309 (1989).
Azuma Makoto
Hashiguchi Yuji
Iwai Kumiko
Kondo Susumu
Seri Shigemi
Hollinden Gary E.
Hollrah Glennon A.
Nihon Medi+Physics Co., Ltd.
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