Low molecular weight heparin fragments as inhibitors of compleme

Details Low molecular weight heparin fragments as inhibitors of compleme Low molecular weight heparin fragments as inhibitors of compleme

1987-06-17

1989-07-11

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 1312, A61K 31725

Patent

active

048473383

ABSTRACT:
There is disclosed a tetrasaccharide, a hexasaccharide, on octasaccharide and a decasaccharide all capable of inhibiting complement activation and having less tha 33% of undigested native heparin's anticoagulation activity.

REFERENCES:
patent: 3636282 (1972-01-01), Klein
patent: 3766167 (1973-10-01), Lasker et al.
patent: 4098995 (1978-07-01), Gopalannair et al.
patent: 4240163 (1980-12-01), Galin
patent: 4607025 (1986-08-01), Petiton et al.
Chem Abst, 103:4756w, 1985.
Chem Abst. 103:326f, 1985.

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